Wow. It's a bold prediction. Houston's offense if they all can stay healthy will be in alot of games this season. Their defense has the talent there, but needs to step it up.
The 49er's on the other hand are responding well to Mike Singletary. If they can run the ball successfully, they will be able to manage the game and clock better in their favor. Last year when Mike Sing took over, the defense looked SHARP! Now that they have switched to a 3-4 permanantly and simplified their defense I do expect them to continue what they did the past 4-5 games of last season.
Btw, did I mention this was a BOLD prediction?