sin2am

Model: GL-21M
Features
For processing large sample volumes rapidly and reliably in a single run
Quickly separates large volumes of suspension with high yields
Ideal for plant/animal/bacteria cell harvesting, protein precipitation, cell enrichment, vaccine production, sediment extraction from water samples
Fast, Efficient Separations
Advanced spindle drive technology delivers rapid acceleration and quick braking to speed throughput and extend instrument life
Quiet operation
High g-forces for faster separations over a wider range of applications
Dual lid-locking for improved safety
Continuous Imbalance Tolerance Protects Samples
Detects excessive speed and signals maximum permissible value for rotor
Smart, Intuitive Controls
Easy control panel is intuitive and simple to navigate
Stores 30 programs for most-used run parameters
Pre-cool program for rapid cooling
Continuous Flow Rotors
Max Capacity: 3000ml
Max. Speed: 16,000rpm
Max. RCF: 28,200 x g
Rotor type: 4 options
Technical Data
ModelGL-21M
ScreenLED & LCD color screen
Max. Speed21000rpm
Max. RCF47400xg
Max.Capacity6x500ml
Temp.range(at RT 25鈩?-20鈩儈40鈩?/p>
Temp accuracy卤1鈩?/p>
Speed accuracy卤20rpm
Timer range1~99h59min
Acceleration Rates1~10
Deceleration Rates1~10
MotorConverter Motor, direct drive
ControlMicroprocessor Control
Power supplyAC220v 50hz 30A
Net weight220kg
Gross weight310kg
Dimension860脳730脳1200mm(L脳W脳H)
Packing Size1000脳850脳1400mm(L脳W脳H)
Rotor List
No.10 Continuous RotorMax speed : 14000r/min
Capacity : 1000ml
Max rcf : 21500xg
Material:Lc
No.11 Continuous RotorMax speed : 16000r/min
Capacity : 1000ml
Max rcf : 28200xg
Material:Ti
No.12 Continuous RotorMax speed : 8000r/min
Capacity : 3000ml
Max rcf : 9530xg
Material:Lc
No.13 Continuous RotorMax speed : 10000r/min
Capacity : 3000ml
Max rcf : 14800xg
Material:Ti
Operation of Continuous Flow Centrifuges GL-21M
Continuous flow centrifuges GL-21M functions on a batch-processing, continuous flow basis.
It means a batch of particle-containing liquid constantly flows into the rotor, which is running at the chosen operating speed.
Particles sediment out of the flowing stream, which then emerges as a particle-depleted effluent and this continues until the rotor鈥檚 particle-containing capacity is reached or until the starting material (the sample) is fully processed.
Therefore, the concentration of the particles the sample contains, as well as its volume govern the amount of starting material that can be managed in a single run. The particle-depleted effluent, the sediment, or both can be collected, just as one collects the sediment, supernatant, or both, following differential centrifugation in conventional swinging bucket or fixed-angle rotors.
Overview of Continuous Flow Centrifugation
In conventional centrifugation rotors, material processing involves a number of tedious steps, which need to be repeated until the whole sample has been processed.
If the amount of material to be processed is large, its rate of sedimentation low, the deceleration/acceleration time of the rotor long, and the capacity of the rotor small, then conventional processing of large volumes of material will be labor-intensive and take up a significant amount of time.
One process that reduces material processing time is continuous flow centrifugation. In this process, large volumes of material can be centrifuged at high centrifugal forces without having to fill and decant a large number of centrifuge tubes or frequently stop and start the rotor.
For instance, the continuous flow method can process 10L of liquid containing 500S particles in 4h or less, depending on the type of rotor chosen. However, the same operation would take 12 to 21 hours with conventional batch-type centrifugation.
The combination of high throughput and high centrifugal force makes continuous flow processing especially useful for:
Pelleting of subcellular fractions
Sedimentation of bacteria
Large-scale collection of viruses for commercial vaccine preparation or for research purposes
Nonetheless, continuous flow centrifugation does not necessarily need to be confined to biomedical applications and should be considered when any type of particles with sedimentation coefficients of 50 S or more need to be routinely separated from fluid volumes of 2L or more. Continuous flow rotors considerably reduce material processing time for two reasons:
Their capacities are large, meaning they do not need to be stopped and started as frequently as conventional rotors do. As a result, sample handling time is reduced and the time spent waiting for rotor deceleration and acceleration between the runs is reduced.
Their short path lengths minimize the overall pelleting time. Therefore, they efficiently pellet solids out of a sample stream and facilitate a rapid flow of material through the rotor.
Qualifying the Sample
Continuous flow rotors offer the most benefit over conventional rotors if the sample possesses the following properties:
A low solid:liquid ratio (5 to 15%). If this ratio is above 15%, the rotor is likely to be over efficient.
The particles鈥?sedimentation coefficient is more than 50 SContinuous Flow Centrifuge
website:http://www.hncentrifuge.com/continuous-flow-centrifuge/